Version One
Antidote was created by a small team of dedicated SoulMasters, who researched the old flora and fauna of the Dream. The head researcher, Juras, was credited with the actual creation of the Art. It was long known that certain plants could poison, and that Dreamers could do the same. Thus, they worked carefully on several solutions to the problem, then testing them on unsuspecting victims. After causing a few Dreamers to mysteriously change gender, and causing others to lose hair, they finally found a set of elements that when combined would erase any trace of poison in a Dreamer. Juras then found a way to transform this combination of elements into Art form, so that his Focus could evoke it. However, one must be fairly powerful to control this delicate healing Art.
Version Two
This tale was heard being told by Balthiir.
In a past age, when dreamers first began to was amongst themselves there arose two Dreamwrights of equal skill and opposite purpose. The Dreamwright Yabnuk was a dark man taken to fulfillment of dark passions. Revenge, plotting, skullduggery; these were his meat and bread. The Dreamwright Theofanes was a pacifist, he believed that only through peace, could the true path of concordance in the city be found. His favorite past time was tending his garden in Cloudsbreak. In art they had few equals, however as you might imagine, their ways were diametrically opposed. In time Theofanes took an apprentice, a young dreamer named Alortes. Herein lies the crux of the matter. You see, Alortes made the mistake of standing between Yabnuk and his vengeance. Yabnuk could not defeat Alortes with the arts he knew, for Alortes was skilled in the arts that protected a dreamer from harm and restored vigor to the injured. Yabnuk returned to his studies once more, he studied things in the dream which brought weakness, sickness and corruption. From these things he learned to bring about a sickness in his fellow dreamers, a poisoning of the soul. With his power, Yabnuk confronted Alortes. Alortes escaped, but the poison still coursed through his veins. Alortes staggered back to the refuge of his master, leaking essence the whole way. In shock and dismay, Theofanes twisted the art of Drain Self to work in reverse and took the poison upon himself so he might overcome it with his strength and training. It took days before Theofanes found a way to rid himself of the poison, but the day did come. through his willingness and self sacrifice, Theofanes countered the poison that Yabnuk had wrought in anger. Determined that no other should suffer, Theofanes spread the Knowledge to others and thus engendered the art we know today as Antidote.